วัน: 9 ตุลาคม 2025

HONG KONG, Oct 9, 2025 - (ACN Newswire via SeaPRwire.com) - Everest Medicines today announced that the results of its Asian multicenter Phase III ENLIGHT UC study (ES101002) of etrasimod (VELSIPITY(R)) for the treatment of subjects with moderately to severely active ulcerative colitis (UC) have been published in the prestigious international journal The Lancet Gastroenterology & Hepatology, marking the global recognition of this next-generation selective S1P receptor modulator’s efficacy in Asian patients.The published results are from the ENLIGHT UC study (ES101002), a multicenter, randomized, double-blind, placebo-controlled Phase III trial of etrasimod conducted across Asia. ENLIGHT is the largest completed Phase III trial to date in Asian patients with moderately to severely active UC, enrolling 340 eligible subjects who were randomized to receive once-daily etrasimod or placebo for 12 weeks of induction treatment. All patients had an inadequate response or intolerance to at least one conventional, biologic, or Janus kinase (JAK) inhibitor therapy.The study results showed that, during both the 12-week induction phase and the 40-week maintenance phase, etrasimod demonstrated statistically significant and clinically meaningful improvements across all primary and secondary efficacy endpoints. The safety profile of etrasimod was consistent with previous studies, with no new safety signals observed.Prof. Wu Kaichun at the First Affiliated Hospital of AFMU who is the principal investigator for etrasimod’s Asia clinical trial said: “As the largest Phase III trial of UC in Asia, the results fill the gap in clinical data on active UC in Asia. The results confirm that etrasimod shows good efficacy and safety in Asian patients including Chinese patients, with positive effects on improving clinical symptoms and promoting endoscopic improvement.”“Publication of the ENLIGHT UC study in The Lancet Gastroenterology & Hepatology underscores etrasimod’s strong clinical value in the treatment of moderately to severely active UC and providing stronger clinical evidence to support patients across Asia.” said Rogers Yongqing Luo, Chief Executive Officer of Everest Medicines.“The company initiated local production of etrasimod in March and remains committed to accelerating the regulatory approval process in Mainland China and other Asian markets, helping more patients achieve higher-quality, longer-lasting disease remission.”VELSIPITY(R) has been approved in Singapore, Macao SAR, and Hong Kong SAR. Its NDA has also been accepted in South Korea and Taiwan, China. In December 2024, China’s National Medical Products Administration (NMPA) officially accepted the NDA for VELSIPITY(R), with approval expected in the first half of 2026. As Everest’s third commercialized product, VELSIPITY(R) has been approved by the Guangdong Provincial Medical Products Administration for adult patients with moderately to severely active UC, and is now available at medical institutions designated under the Connect Policy in the Greater Bay Area. The localized production project for VELSIPITY(R) was officially launched at the Jiashan manufacturing site in March 2025, providing strong support for its future commercialization.As a core product of Everest Medicines, etrasimod is an innovative and advanced therapy that provides rapid onset of action, clinical remission and endoscopic improvement through an oral, once-daily regimen. Following its inclusion in the American Gastroenterological Association (AGA) Clinical Practice Guideline as a first-line treatment for ulcerative colitis in December 2024, etrasimod was included in the American College of Gastroenterology (ACG) Clinical Guideline Update in June 2025, strongly recommended for both induction and maintenance of remission in patients with moderately to severely active UC.From the market perspective, the number of UC patients in Asia is rising rapidly, while treatment options remain relatively limited. In China alone, the UC patient population was estimated at approximately 800,000 in 2024 and is projected to reach 1.5 million by 2031. With its proven efficacy and safety, VELSIPITY(R) is expected to quickly enter and reshape the market landscape. To ensure accessibility and supply stability, Everest has launched a localized production project at its Jiashan manufacturing site, with an expected annual production capacity of up to 50 million tablets to enhance supply stability and cost efficiency.Notably, in late August Everest launched a proactive build-up of its commercial team for etrasimod, with the team expected to expand significantly around the time of approval. This deployment will not only ensure the efficient commercialization of VELSIPITY(R) upon launch, but also lay a solid foundation for future inclusion in the National Reimbursement Drug List (NRDL) and large-scale uptake.Industry observers widely expect VELSIPITY(R) to become Everest’s next blockbuster product, with analysts projecting peak sales of up to RMB 5 billion. As VELSIPITY(R) realizes its commercial potential, Everest’s revenue mix and growth trajectory are expected to strengthen further, providing greater visibility and confidence for long-term investors. Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

SINGAPORE, Oct 9, 2025 - (ACN Newswire via SeaPRwire.com) - GoDaddy, a global leader in empowering entrepreneurs, announced the expansion of its new Digital Ads feature with GoDaddy Airo® to nine new English-language markets including Ireland, Malaysia, New Zealand, Pakistan, Philippines, Singapore, South Africa and the United Arab Emirates.This AI-powered tool enables small business owners and entrepreneurs to create, launch, and manage professional Google Ad campaigns in minutes, without prior advertising expertise, directly addressing a key barrier to online visibility and customer acquisition."Reaching new customers online is critical for growth, but creating effective ads has traditionally required significant time or resources many small businesses simply don’t have," said Selina Bieber, Vice President of International Markets at GoDaddy."Airo Digital Ads now empowers entrepreneurs in these markets to compete more effectively. Our AI handles the technical complexities, like writing compelling ad copy and selecting high-performing search keywords, so they can focus on running their business and connecting with customers."Why Simplifying Digital Ads MattersGoDaddy’s 2025 Global Entrepreneurship Survey highlights the hurdles faced by entrepreneurs, with over one in three (37%) facing financial constraints limiting marketing investments, 23% struggling with technology complexity, and 40% citing work-life balance challenges from operational demands.Digital Ads leverages Airo’s advanced AI to transform ad creation from a daunting task into an effortless streamlined process.* Instant Campaign Setup: Generate complete, professional Google Ad campaigns in minutes. Airo drafts persuasive ad copy, selects relevant keywords based on the business offering, and structures the campaign using industry best practices, eliminating the "blank page" problem.* Zero Experience Required: Tailored specifically for those new to digital advertising, the intuitive dashboard guides users through the process without requiring a dedicated marketing team.* Full Control & Customization: Users review, edit, and perfect every element before launch – headlines, descriptions, keywords, target audience, and budget. The AI provides a powerful starting point, but the business owner makes the final decisions.* Integrated Management & Analytics: Launch campaigns and track detailed performance metrics (like clicks, impressions, and costs) all within the GoDaddy Digital Ads dashboard. No need to juggle multiple platforms or logins.* Risk-Free Testing: Preview the complete ad exactly as it will appear on Google. Make unlimited adjustments. Campaigns only go live when the user is completely satisfied.AI Benefits for All EntrepreneursDigital Ads effectively works as a plug-and-play solution to key challenges faced by various entrepreneurial segments. Small business owners new to digital ads gain a streamlined, cost-efficient entry point without agency overhead; busy entrepreneurs benefit from rapid campaign launch to drive traffic while juggling multiple priorities; and budget-conscious businesses garner professional results without the need to hire specialists to manage ads.Get started today at getstarted.godaddy/APAC.About GoDaddyGoDaddy helps millions of entrepreneurs globally start and scale their businesses. People come to GoDaddy to name their idea, build a website and logo, sell their products and services, and accept payments. GoDaddy Airo®, the company’s AI-powered experience, makes growing a small business faster and easier by helping them to get their idea online in minutes, drive traffic and boost sales. GoDaddy’s expert guides are available 24/7 to provide assistance. To learn more about the company, visit www.GoDaddy.com.Issued on behalf of GoDaddy.For more information, contact:Fekra Communicationsinfo@fekracomms.com Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

WATERLOO, ONTARIO, Oct 9, 2025 - (ACN Newswire via SeaPRwire.com) - BlackBerry Limited (NYSE:BB)(TSX:BB) today announced the expansion of BlackBerry® SecuSUITE® to Windows® devices, extending sovereign-grade secure communications trusted by governments and critical enterprises to include laptops and workstations. This expansion will enable secure voice, messaging, and file sharing across mobile devices, laptops, and desktops, delivering the same assured protection through a consistent, adoptable workflow.For end users, this means they will be able to collaborate securely from whichever device best suits their task - on the move, at a primary workstation, or working from a laptop - without changing the way they operate. They can review documents on a larger screen, compose detailed messages with a keyboard, or coordinate quickly in the field verbally, with all forms of communication working together to support a continuous flow from decision to action. SecuSUITE keeps workflows simple while helping to ensure every exchange stays protected.For organizations, extending the SecuSUITE solution's independently certified architecture to include Windows laptops and workstations enables mission-critical communications to remain secure as teams move between endpoints and networks. Communications will be shielded from eavesdropping, identity spoofing, and metadata exploitation, while deployment flexibility (on-premises, private cloud, or hosted) will allow agencies to retain full sovereignty and control over their data."Critical conversations don't strictly happen in the field," said Dr. Christoph Erdmann, Senior Vice President, BlackBerry. "By expanding SecuSUITE to include Windows devices, we're giving users the same sovereign-grade protection they rely on during mobile operations, now extended to their primary workstation or laptop. This helps ensure critical communications stay protected and keep moving, fitting naturally into everyday operations and encouraging adoption without adding complexity."SecuSUITE is independently and vastly certified, with validations from NIAP, NATO Restricted, BSI, and CSfC, and is trusted by governments and critical enterprises worldwide to protect their most sensitive communications. As a core pillar of BlackBerry® Secure Communications, SecuSUITE extends this assurance to secure voice, messaging, file sharing, and crisis coordination - providing full sovereign control over how and where systems are deployed. BlackBerry Secure Communications is trusted by governments, defense agencies, and critical industries worldwide, including all G7 governments, 18 of the G20 members and 8 of the top 10 global banks, to protect sensitive conversations and large-scale coordination.AvailabilityThe Windows expansion of SecuSUITE will be generally available in November 2025 as BlackBerry® SecuSUITE® for Windows Desktop.About BlackBerryBlackBerry (NYSE:BB)(TSX:BB) provides enterprises and governments the intelligent software and services that power the world around us. Based in Waterloo, Ontario, the company's high-performance foundational software enables major automakers and industrial giants alike to unlock transformative applications, drive new revenue streams and launch innovative business models, all without sacrificing safety, security, and reliability. With a deep heritage in Secure Communications, BlackBerry delivers operational resiliency with a comprehensive, highly secure, and extensively certified portfolio for mobile fortification, mission-critical communications, and critical events management.For more information, visit BlackBerry.com and follow @BlackBerry. Trademarks, including but not limited to BLACKBERRY and EMBLEM Design, are the trademarks or registered trademarks of BlackBerry Limited, and the exclusive rights to such trademarks are expressly reserved. All other trademarks are the property of their respective owners. BlackBerry is not responsible for any third-party products or services.Media Contacts:BlackBerry Media Relations+1 (519) 597-7273mediarelations@BlackBerry.comSOURCE: BlackBerry Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

- ULI relocates to a premium new office space at The Executive Centre, embracing a flexible and hybrid work model.- The move-in marked a significant milestone for ULI’s mission to prioritise sustainability and represent the future of work.- This partnership with The Executive Centre strengthens both organisations' commitment to improving urban environments and inspiring cross functional partnerships in the real estate sector.HONG KONG, Oct 9, 2025 - (ACN Newswire via SeaPRwire.com) - The Urban Land Institute (ULI), the oldest and largest network of cross-disciplinary real estate and land use experts in the world, has officially moved its Asia-Pacific headquarters to The Executive Centre’s location at 28 Stanley Street, Central, Hong Kong. The relocation was celebrated with a vibrant move-in party on September 26, 2025, marking a significant milestone in ULI’s commitment to fostering innovation and cross functional collaboration within the real estate sector.With over 45,000 members worldwide, ULI is dedicated to shaping the future of the built environment, working alongside industry leaders to transform communities into livible, breathable and more human-centric environments. This strategic move reflects ULI’s forward-thinking approach, embracing a flexible and hybrid workspace model that aligns with contemporary work trends."This move represents a pivotal moment for ULI as we seek to enhance our impact in the region and extend our partnerships within the corporate real estate sector," stated Alan Beebe, CEO Asia Pacific of ULI. "By situating ourselves in a dynamic environment like The Executive Centre, we can better serve our members and advance our mission to improve urban spaces."The Executive Centre is equally enthusiastic about this collaboration. "Welcoming ULI to our centre at 28 Stanley Street is a testament to our commitment to providing exceptional premium flexible workspaces that facilitate business growth and collaboration," said Jennifer So, City Head of Hong Kong at The Executive Centre. "This partnership aligns seamlessly with our vision of supporting organisations dedicated to elevating the built environment and enhancing the future of work."The new office model features a blend of private office and coworking access, along with the utilisation of TEC’s collaborative shared lounges and event spaces, reflecting a trend among global organisations seeking to optimise their workspace for collaboration and flexibility. This strategic partnership between ULI and TEC is poised to cultivate broader collaboration between ULI Members and TEC’s alike, with both organisations dedicated to improving urban environments and defining the evolution of workspaces.As ULI embarks on this new chapter, TEC looks forward to engaging with the community and collaborating on initiatives that enhance the quality of life in urban settings.About The Executive CentreThe Executive Centre (TEC) is a premium flexible workspace provider, opened its doors in Hong Kong in 1994 and has over 240+ Centres in 37 cities and 15 markets.The Executive Centre caters to professionals and industry leaders. TEC has a global network spanning Greater China, Southeast Asia, North Asia, India, Sri Lanka, the Middle East, and Australia. Each Executive Centre offers a prestigious address with the advanced infrastructure to meet the needs of its Members.Privately owned and headquartered in Hong Kong, TEC provides Private and Shared Workspaces, Business Services, and Meeting & Events facilities to suit its clients’ business' needs.www.executivecentre.comAbout Urban Land InstituteThe Urban Land Institute is a global, member-driven organization comprising more than 45,000 real estate and urban development professionals dedicated to advancing the Institute’s mission of shaping the future of the built environment for transformative impact in communities worldwide.Since 1936, ULI has been a source for best practices and impartial information, and a forum in which real estate industry leaders can share ideas, experiences, and best practices.ULI members represent the entire spectrum of land use and real estate development disciplines working in private enterprise and public service. They benefit from and contribute to a body of knowledge and a global network that shapes every aspect of the built environment.Press EnquiriesThe Executive CentrePebble LeePebble_lee@executivecentre.com / +852 3951 9888 Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com